The Early Antibody-Dependent Cell-Mediated Cytotoxicity Response Is Associated With Lower Viral Set Point in Individuals With Primary HIV Infection

The Early Antibody-Dependent Cell-Mediated Cytotoxicity Response Is Associated With Lower Viral Set Point in Individuals With Primary HIV Infection

Antibody-dependent cell-mediated cytotoxicity (ADCC) is an immune response largely mediated by natural killer (NK) cells that can lyse target cells and combat tumors and viral infections. However, the role of ADCC in response to primary HIV infection is poorly understood. In the present study, we ex...

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Bibliographic Details
Main Authors: Xi Chen, Meilin Lin, Shi Qian, Zining Zhang, Yajing Fu, Junjie Xu, Xiaoxu Han, Haibo Ding, Tao Dong, Hong Shang, Yongjun Jiang
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-10-01
Series:Frontiers in Immunology
Subjects:
human immunodeficiency virus
natural killer cells
primary HIV infection
antibody-dependent cell-mediated cytotoxicity
epitopes
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2018.02322/full

Internet

https://www.frontiersin.org/article/10.3389/fimmu.2018.02322/full

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