Protective Effect of Lafutidine, a Novel H2-Receptor Antagonist, on Reflux Esophagitis in Rats Through Capsaicin-Sensitive Afferent Neurons
ABSTRACT: We examined the effect of lafutidine, a novel histamine H2-receptor antagonist, on acid reflux esophagitis in rats in relation to capsaicin-sensitive afferent neurons. The esophagitis was induced in rats by ligating both the pylorus and forestomach for 4 h. Lafutidine (1 – 30 mg/kg) and ci...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Elsevier
2003-01-01
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| Series: | Journal of Pharmacological Sciences |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S1347861319326155 |