Future Trends in the Pharmacogenomics of Brain Disorders and Dementia: Influence of APOE and CYP2D6 Variants

Future Trends in the Pharmacogenomics of Brain Disorders and Dementia: Influence of APOE and CYP2D6 Variants

About 80% of functional genes in the human genome are expressed in the brain and over 1,200 different genes have been associated with the pathogenesis of CNS disorders and dementia. Pharmacogenetic studies of psychotropic drug response have focused on determining the relationship between variations...

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Bibliographic Details
Main Authors: Antón Álvarez, Verónica Couceiro, Susana Rodríguez, Ángela Casas, Margarita Alcaraz, Laura Nebril, Iván Tellado, Iván Carrera, Lola Corzo, Valter Lombardi, Adam McKay, Juan C. Carril, Ramón Cacabelos, Rocío Martínez-Bouza, Lucía Fernández-Novoa
Format: Article
Language:English
Published: MDPI AG 2010-09-01
Series:Pharmaceuticals
Subjects:
Alzheimer’s disease
APOE
CYPs
genetics
pharmacogenomics
Online Access:http://www.mdpi.com/1424-8247/3/10/3040/

Internet

http://www.mdpi.com/1424-8247/3/10/3040/

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