Integrated imaging of [11C]-PBR28 PET, MR diffusion and magnetic resonance spectroscopy 1H-MRS in amyotrophic lateral sclerosis

Integrated imaging of [11C]-PBR28 PET, MR diffusion and magnetic resonance spectroscopy 1H-MRS in amyotrophic lateral sclerosis

Objective: To determine the relationship between brain tissue metabolites measured by in vivo magnetic resonance spectroscopy (1H-MRS), and glial activation assessed with [11C]-PBR28 uptake in people with amyotrophic lateral sclerosis (ALS). Methods: Forty ALS participants were evaluated clinically...

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Bibliographic Details
Main Authors: Eva-Maria Ratai, Mohamad J. Alshikho, Nicole R. Zürcher, Marco L. Loggia, Catherine L. Cebulla, Paul Cernasov, Beverly Reynolds, Jennifer Fish, Raghav Seth, Suma Babu, Sabrina Paganoni, Jacob M. Hooker, Nazem Atassi
Format: Article
Language:English
Published: Elsevier 2018-01-01
Series:NeuroImage: Clinical
Online Access:http://www.sciencedirect.com/science/article/pii/S2213158218302481

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http://www.sciencedirect.com/science/article/pii/S2213158218302481

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