Effect of polymorphisms in XPD on clinical outcomes of platinum-based chemotherapy for Chinese non-small cell lung cancer patients.

Effect of polymorphisms in XPD on clinical outcomes of platinum-based chemotherapy for Chinese non-small cell lung cancer patients.

PURPOSE: Xeroderma pigmentosum group D (XPD) codes for a DNA helicase involved in nucleotide excision repair that removes platinum-induced DNA damage. Genetic polymorphisms of XPD may affect DNA repair capacity and lead to individual differences in the outcome of patients after chemotherapy. This st...

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Bibliographic Details
Main Authors: Wenting Wu, Huan Li, Huibo Wang, Xueying Zhao, Zhiqiang Gao, Rong Qiao, Wei Zhang, Ji Qian, Jiucun Wang, Hongyan Chen, Qingyi Wei, Baohui Han, Daru Lu
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3315552?pdf=render

Internet

http://europepmc.org/articles/PMC3315552?pdf=render

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