Low serum gastrin associated with ER+ breast cancer development via inactivation of CCKBR/ERK/P65 signaling

Low serum gastrin associated with ER+ breast cancer development via inactivation of CCKBR/ERK/P65 signaling

Abstract Background Gastrin is an important gastrointestinal hormone produced primarily by G-cells in the antrum of the stomach. It normally regulates gastric acid secretion and is implicated in a number of human disease states, but how its function affects breast cancer (BC) development is not docu...

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Bibliographic Details
Main Authors: Li-Li Meng, Jing-Long Wang, Shu-Ping Xu, Li-Dong Zu, Zhao-Wen Yan, Jian-Bing Zhang, Ya-Qin Han, Guo-Hui Fu
Format: Article
Language:English
Published: BMC 2018-08-01
Series:BMC Cancer
Subjects:
Gastrin
Breast cancer
ER
ERK
P65
Online Access:http://link.springer.com/article/10.1186/s12885-018-4717-7

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http://link.springer.com/article/10.1186/s12885-018-4717-7

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