Integrated genomic and epigenomic analysis of breast cancer brain metastasis.

Integrated genomic and epigenomic analysis of breast cancer brain metastasis.

The brain is a common site of metastatic disease in patients with breast cancer, which has few therapeutic options and dismal outcomes. The purpose of our study was to identify common and rare events that underlie breast cancer brain metastasis. We performed deep genomic profiling, which integrated...

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Bibliographic Details
Main Authors: Bodour Salhia, Jeff Kiefer, Julianna T D Ross, Raghu Metapally, Rae Anne Martinez, Kyle N Johnson, Danielle M DiPerna, Kimberly M Paquette, Sungwon Jung, Sara Nasser, Garrick Wallstrom, Waibhav Tembe, Angela Baker, John Carpten, Jim Resau, Timothy Ryken, Zita Sibenaller, Emanuel F Petricoin, Lance A Liotta, Ramesh K Ramanathan, Michael E Berens, Nhan L Tran
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3906004?pdf=render

Internet

http://europepmc.org/articles/PMC3906004?pdf=render

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