Multiple variants in XDH and MOCOS underlie xanthine urolithiasis in dogs

Multiple variants in XDH and MOCOS underlie xanthine urolithiasis in dogs

Hereditary xanthinuria is a rare autosomal recessive disease caused by missense and loss of function variants in the xanthine dehydrogenase (XDH) or molybdenum cofactor sulfurase (MOCOS) genes. The aim of this study was to uncover variants underlying risk for xanthinuria in dogs. Affected dogs inclu...

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Bibliographic Details
Main Authors: Nicole M. Tate, Katie M. Minor, Jody P. Lulich, James R. Mickelson, Allyson Berent, Jonathan D. Foster, Kasey H. Petersen, Eva Furrow
Format: Article
Language:English
Published: Elsevier 2021-12-01
Series:Molecular Genetics and Metabolism Reports
Subjects:
Xanthine dehydrogenase
Molybdenum cofactor sulfurase
Hereditary xanthinuria
Canine genetics
Kidney stones
Nephrolithiasis
Online Access:http://www.sciencedirect.com/science/article/pii/S2214426921000860

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http://www.sciencedirect.com/science/article/pii/S2214426921000860

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