MicroRNA-27 Prevents Atherosclerosis by Suppressing Lipoprotein Lipase-Induced Lipid Accumulation and Inflammatory Response in Apolipoprotein E Knockout Mice.

MicroRNA-27 Prevents Atherosclerosis by Suppressing Lipoprotein Lipase-Induced Lipid Accumulation and Inflammatory Response in Apolipoprotein E Knockout Mice.

Atherosclerotic lesions are lipometabolic disorder characterized by chronic progressive inflammation in arterial walls. Previous studies have shown that macrophage-derived lipoprotein lipase (LPL) might be a key factor that promotes atherosclerosis by accelerating lipid accumulation and proinflammat...

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Bibliographic Details
Main Authors: Wei Xie, Liang Li, Min Zhang, Hai-Peng Cheng, Duo Gong, Yun-Cheng Lv, Feng Yao, Ping-Ping He, Xin-Ping Ouyang, Gang Lan, Dan Liu, Zhen-Wang Zhao, Yu-Lin Tan, Xi-Long Zheng, Wei-Dong Yin, Chao-Ke Tang
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4892477?pdf=render

Internet

http://europepmc.org/articles/PMC4892477?pdf=render

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