Chronic Porphyromonas gingivalis infection accelerates the occurrence of age-related granules in ApoE–/– mice brains

Chronic Porphyromonas gingivalis infection accelerates the occurrence of age-related granules in ApoE–/– mice brains

This study explored the origin of age-related granules in the apolipoprotein E gene knockout (ApoE−/−) B6 background mice brains following chronic gingival infection with Porphyromonas gingivalis for 24 weeks. Intracerebral localization of P. gingivalis was detected by fluorescence in situ hybridiza...

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Bibliographic Details
Main Authors: Sim K. Singhrao, Sasanka Chukkapalli, Sophie Poole, Irina Velsko, St John Crean, Lakshmyya Kesavalu
Format: Article
Language:English
Published: Taylor & Francis Group 2017-01-01
Series:Journal of Oral Microbiology
Subjects:
Age-related granules
blood–brain barrier damage
infection
inflammation
injury
Online Access:http://dx.doi.org/10.1080/20002297.2016.1270602

Internet

http://dx.doi.org/10.1080/20002297.2016.1270602

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