Pancreatic insulin-producing cells differentiated from human embryonic stem cells correct hyperglycemia in SCID/NOD mice, an animal model of diabetes.

Pancreatic insulin-producing cells differentiated from human embryonic stem cells correct hyperglycemia in SCID/NOD mice, an animal model of diabetes.

BACKGROUND:Human pancreatic islet transplantation is a prospective curative treatment for diabetes. However, the lack of donor pancreases greatly limits this approach. One approach to overcome the limited supply of donor pancreases is to generate functional islets from human embryonic stem cells (hE...

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Bibliographic Details
Main Authors: Xiu-feng Hua, Yan-wei Wang, Yu-xiao Tang, Sheng-qiang Yu, Shao-hua Jin, Xiao-mei Meng, Hua-feng Li, Fu-jun Liu, Qiang Sun, Hai-yan Wang, Jian-yuan Li
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4092102?pdf=render

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http://europepmc.org/articles/PMC4092102?pdf=render

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