Competitive ELISA for a serologic test to detect dengue serotype-specific anti-NS1 IgGs using high-affinity UB-DNA aptamers

Abstract Serologic tests to detect specific IgGs to antigens related to viral infections are urgently needed for diagnostics and therapeutics. We present a diagnostic method for serotype-specific IgG identification of dengue infection by a competitive enzyme-linked immunosorbent assay (ELISA), using...

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Bibliographic Details
Main Authors: Ken-ichiro Matsunaga, Michiko Kimoto, Vanessa Weixun Lim, Tun-Linn Thein, Shawn Vasoo, Yee-Sin Leo, William Sun, Ichiro Hirao
Format: Article
Language:English
Published: Nature Publishing Group 2021-09-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-021-97339-8