Noncatalytic Function of a JmjC Domain Protein Disrupts Heterochromatin

Chromatin-modifying enzymes are frequently overexpressed in cancer cells, and their enzymatic activities play important roles in changing the epigenetic landscape responsible for tumorigenesis. However, many of these proteins also execute noncatalytic functions, which are poorly understood. In fissi...

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Bibliographic Details
Main Authors: Kehan Bao, Songtao Jia
Format: Article
Language:English
Published: SAGE Publishing 2019-07-01
Series:Epigenetics Insights
Online Access:https://doi.org/10.1177/2516865719862249