Noncatalytic Function of a JmjC Domain Protein Disrupts Heterochromatin
Chromatin-modifying enzymes are frequently overexpressed in cancer cells, and their enzymatic activities play important roles in changing the epigenetic landscape responsible for tumorigenesis. However, many of these proteins also execute noncatalytic functions, which are poorly understood. In fissi...
Main Authors: | , |
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Format: | Article |
Language: | English |
Published: |
SAGE Publishing
2019-07-01
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Series: | Epigenetics Insights |
Online Access: | https://doi.org/10.1177/2516865719862249 |