A Conserved Tryptophan in the Ebola Virus Matrix Protein C-Terminal Domain Is Required for Efficient Virus-Like Particle Formation

A Conserved Tryptophan in the Ebola Virus Matrix Protein C-Terminal Domain Is Required for Efficient Virus-Like Particle Formation

The Ebola virus (EBOV) harbors seven genes, one of which is the matrix protein eVP40, a peripheral protein that is sufficient to induce the formation of virus-like particles from the host cell plasma membrane. eVP40 can form different structures to fulfil different functions during the viral life cy...

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Bibliographic Details
Main Authors: Kristen A. Johnson, Rudramani Pokhrel, Melissa R. Budicini, Bernard S. Gerstman, Prem P. Chapagain, Robert V. Stahelin
Format: Article
Language:English
Published: MDPI AG 2020-05-01
Series:Pathogens
Subjects:
Ebola virus
lipid–protein interaction
oligomerization
phosphatidylserine
phosphatidylinositol-4,5-bisphosphate
tryptophan
Online Access:https://www.mdpi.com/2076-0817/9/5/402

Internet

https://www.mdpi.com/2076-0817/9/5/402

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