Comprehensive evaluation of one-carbon metabolism pathway gene variants and renal cell cancer risk.

Comprehensive evaluation of one-carbon metabolism pathway gene variants and renal cell cancer risk.

Folate and one-carbon metabolism are linked to cancer risk through their integral role in DNA synthesis and methylation. Variation in one-carbon metabolism genes, particularly MTHFR, has been associated with risk of a number of cancers in epidemiologic studies, but little is known regarding renal ca...

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Bibliographic Details
Main Authors: Todd M Gibson, Paul Brennan, Summer Han, Sara Karami, David Zaridze, Vladimir Janout, Helen Kollarova, Vladimir Bencko, Marie Navratilova, Neonila Szeszenia-Dabrowska, Dana Mates, Alena Slamova, Ruth M Pfeiffer, Rachael Z Stolzenberg-Solomon, Susan T Mayne, Meredith Yeager, Stephen Chanock, Nat Rothman, Wong-Ho Chow, Philip S Rosenberg, Paolo Boffetta, Lee E Moore
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3198392?pdf=render

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http://europepmc.org/articles/PMC3198392?pdf=render

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