Reconciling diverse mammalian pigmentation patterns with a fundamental mathematical model
How embryonic melanoblast behaviour influences adult pigmentation patterns and causes patterning defects is unclear. Here, Mort et al. construct a stochastic model parameterised experimentally to show that melanoblast migration is undirected and that reduced proliferation causes patterning defects.
Main Authors: | , , , , , , , , , |
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Format: | Article |
Language: | English |
Published: |
Nature Publishing Group
2016-01-01
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Series: | Nature Communications |
Online Access: | https://doi.org/10.1038/ncomms10288 |