Pharmaceutical efficacy of harmalol in inhibiting hepatocellular carcinoma

Abstract Background Diethylnitrosamine (DEN) promoted by carbon tetrachloride (CCl4) forms DNA adducts inducing hepatocellular carcinoma (HCC). Plant alkaloid, harmalol, is being used as a therapeutic agent against HCC due to its accessibility and efficacy by apoptosis and inhibiting proliferation o...

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Bibliographic Details
Main Authors: Sarita Sarkar, Paromita Bhattacharjee, Tapas Ghosh, Kakali Bhadra
Format: Article
Language:English
Published: SpringerOpen 2020-07-01
Series:Future Journal of Pharmaceutical Sciences
Subjects:
DEN
HCC
Online Access:http://link.springer.com/article/10.1186/s43094-020-00045-x