Characterization and Genetic Analyses of New Genes Coding for NOD2 Interacting Proteins.

Characterization and Genetic Analyses of New Genes Coding for NOD2 Interacting Proteins.

NOD2 contributes to the innate immune response and to the homeostasis of the intestinal mucosa. In response to its bacterial ligand, NOD2 interacts with RICK and activates the NF-κB and MAPK pathways, inducing gene transcription and synthesis of proteins required to initiate a balanced immune respon...

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Bibliographic Details
Main Authors: Raphaële Thiébaut, Sophie Esmiol, Patrick Lecine, Batoul Mahfouz, Aurelie Hermant, Cendrine Nicoletti, Stephane Parnis, Julie Perroy, Jean-Paul Borg, Leigh Pascoe, Jean-Pierre Hugot, Vincent Ollendorff
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC5094585?pdf=render

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http://europepmc.org/articles/PMC5094585?pdf=render

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