Gelsolin Contributes to the Motility of A375 Melanoma Cells and This Activity Is Mediated by the Fibrous Extracellular Matrix Protein Profile

Skin melanocytes reside on the basement membrane (BM), which is mainly composed of laminin, collagen type IV, and proteoglycans. For melanoma cells, in order to invade into the skin, melanocytes must cross the BM. It has been reported that changes in the composition of the BM accompany melanocytes t...

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Bibliographic Details
Main Authors: Ewa Mazurkiewicz, Aleksandra Makowiecka, Ewa Mrówczyńska, Iryna Kopernyk, Dorota Nowak, Antonina Joanna Mazur
Format: Article
Language:English
Published: MDPI AG 2021-07-01
Series:Cells
Subjects:
Online Access:https://www.mdpi.com/2073-4409/10/8/1848