Comparison of Surrogate Markers of the Type I Interferon Response and Their Ability to Mirror Disease Activity in Systemic Lupus Erythematosus

Comparison of Surrogate Markers of the Type I Interferon Response and Their Ability to Mirror Disease Activity in Systemic Lupus Erythematosus

ObjectivesType I interferons (IFNs) are central and reflective of disease activity in systemic lupus erythematosus (SLE). However, IFN-α levels are notoriously difficult to measure and the type I IFN gene signature (IGS) is not yet available in clinical routine. This study evaluates galectin-9 and a...

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Bibliographic Details
Main Authors: Helena Enocsson, Jonas Wetterö, Maija-Leena Eloranta, Birgitta Gullstrand, Cecilia Svanberg, Marie Larsson, Anders A. Bengtsson, Lars Rönnblom, Christopher Sjöwall
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-06-01
Series:Frontiers in Immunology
Subjects:
SLE
lupus
biomarker
disease activity
interferon
chemokine
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2021.688753/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2021.688753/full

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