Synthesis of no-carrier-added [188, 189, 191Pt]cisplatin from a cyclotron produced 188, 189, 191PtCl4 2− complex

Abstract We developed a novel method for production of no-carrier-added (n.c.a.) [188, 189, 191Pt]PtIICl4 2− from an Ir target material, and then synthesized n.c.a. [*Pt]cis-[PtIICl2(NH3)2] ([*Pt]cisplatin) from [*Pt]PtIICl4 2−. [*Pt]PtIICl4 2− was prepared as a synthetic precursor of n.c.a. *Pt com...

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Bibliographic Details
Main Authors: Honoka Obata, Katsuyuki Minegishi, Kotaro Nagatsu, Mikako Ogawa, Ming-Rong Zhang
Format: Article
Language:English
Published: Nature Publishing Group 2021-04-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-021-87576-2