TCRβ-expressing macrophages induced by a pathogenic murine malaria correlate with parasite burden and enhanced phagocytic activity.

TCRβ-expressing macrophages induced by a pathogenic murine malaria correlate with parasite burden and enhanced phagocytic activity.

Macrophages express a wide array of invariant receptors that facilitate host defense and mediate pathogenesis during pathogen invasion. We report on a novel population of CD11bhighCD14+F4/80+ macrophages that express TCRβ. This population expands dramatically during a Plasmodium berghei ANKA infecti...

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Bibliographic Details
Main Authors: Miranda S Oakley, Joanna K Chorazeczewski, Maya Aleshnick, Vivek Anantharaman, Victoria Majam, Bhavna Chawla, Timothy G Myers, Qin Su, Winter A Okoth, Kazuyo Takeda, Adovi Akue, Mark KuKuruga, L Aravind, Sanjai Kumar
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2018-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC6059462?pdf=render

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http://europepmc.org/articles/PMC6059462?pdf=render

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