Candidate Single Nucleotide Polymorphism Markers for Arsenic Responsiveness of Protein Targets

Arsenic is a toxic metalloid that causes skin cancer and binds to cysteine residues—a property that could be used to infer arsenic responsiveness of a target protein. Non-synonymous Single Nucleotide Polymorphisms (nsSNPs) result in amino acid substitutions and may alter arsenic binding with cystein...

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Bibliographic Details
Main Authors: Raphael D. Isokpehi, Hari H.P. Cohly, Matthew N. Anyanwu, Rajendram V. Rajnarayanan, Paul B. Tchounwou, Udensi K. Udensi, Barbara E. Graham-Evans
Format: Article
Language:English
Published: SAGE Publishing 2010-01-01
Series:Bioinformatics and Biology Insights
Online Access:https://doi.org/10.4137/BBI.S5498