Next generation MUT-MAP, a high-sensitivity high-throughput microfluidics chip-based mutation analysis panel.

Molecular profiling of tumor tissue to detect alterations, such as oncogenic mutations, plays a vital role in determining treatment options in oncology. Hence, there is an increasing need for a robust and high-throughput technology to detect oncogenic hotspot mutations. Although commercial assays ar...

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Bibliographic Details
Main Authors: Erica B Schleifman, Rachel Tam, Rajesh Patel, Alison Tsan, Teiko Sumiyoshi, Ling Fu, Rupal Desai, Nancy Schoenbrunner, Thomas W Myers, Keith Bauer, Edward Smith, Rajiv Raja
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3962342?pdf=render