A Peptide-Nucleic Acid Targeting miR-335-5p Enhances Expression of Cystic Fibrosis Transmembrane Conductance Regulator (<i>CFTR</i>) Gene with the Possible Involvement of the CFTR Scaffolding Protein NHERF1

A Peptide-Nucleic Acid Targeting miR-335-5p Enhances Expression of Cystic Fibrosis Transmembrane Conductance Regulator (<i>CFTR</i>) Gene with the Possible Involvement of the CFTR Scaffolding Protein NHERF1

(1) Background: Up-regulation of the Cystic Fibrosis Transmembrane Conductance Regulator gene (<i>CFTR</i>) might be of great relevance for the development of therapeutic protocols for cystic fibrosis (CF). MicroRNAs are deeply involved in the regulation of CFTR and scaffolding proteins...

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Bibliographic Details
Main Authors: Anna Tamanini, Enrica Fabbri, Tiziana Jakova, Jessica Gasparello, Alex Manicardi, Roberto Corradini, Alessia Finotti, Monica Borgatti, Ilaria Lampronti, Silvia Munari, Maria Cristina Dechecchi, Giulio Cabrini, Roberto Gambari
Format: Article
Language:English
Published: MDPI AG 2021-01-01
Series:Biomedicines
Subjects:
peptide nucleic acids
cystic fibrosis
microRNAs
miR-335-5p
miRNA targeting
delivery
Online Access:https://www.mdpi.com/2227-9059/9/2/117

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https://www.mdpi.com/2227-9059/9/2/117

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