MiRNA expression in psoriatic skin: reciprocal regulation of hsa-miR-99a and IGF-1R.

<h4>Background</h4>Psoriasis is a complex disease at the cellular, genomic and genetic levels. The role of microRNAs in skin development was shown in a keratinocyte-specific Dicer knockout mouse model. Considering that two main characteristics of psoriasis are keratinocytes hyperprolifer...

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Main Authors: Galya Lerman, Camila Avivi, Corine Mardoukh, Aviv Barzilai, Ariel Tessone, Ben Gradus, Felix Pavlotsky, Iris Barshack, Sylvie Polak-Charcon, Arie Orenstein, Eran Hornstein, Yechezkel Sidi, Dror Avni
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/21687694/?tool=EBI