Brain-specific Drp1 regulates postsynaptic endocytosis and dendrite formation independently of mitochondrial division
Dynamin-related protein 1 (Drp1) divides mitochondria as a mechano-chemical GTPase. However, the function of Drp1 beyond mitochondrial division is largely unknown. Multiple Drp1 isoforms are produced through mRNA splicing. One such isoform, Drp1ABCD, contains all four alternative exons and is specif...
Main Authors: | Kie Itoh, Daisuke Murata, Takashi Kato, Tatsuya Yamada, Yoichi Araki, Atsushi Saito, Yoshihiro Adachi, Atsushi Igarashi, Shuo Li, Mikhail Pletnikov, Richard L Huganir, Shigeki Watanabe, Atsushi Kamiya, Miho Iijima, Hiromi Sesaki |
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Format: | Article |
Language: | English |
Published: |
eLife Sciences Publications Ltd
2019-10-01
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Series: | eLife |
Subjects: | |
Online Access: | https://elifesciences.org/articles/44739 |
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