From the biology of PP2A to the PADs for therapy of Hematologic malignancies

Over the past decades, an emerging role of phosphates in the pathogenesis of hematologic malignancies and solid tumors has been established. The tumor suppressor Protein phosphatase 2A (PP2A) belongs to the serine-threonine phosphatases family and accounts for the majority of serine-threonine phosph...

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Bibliographic Details
Main Authors: Maria eCiccone, George eCalin, Danilo ePerrotti
Format: Article
Language:English
Published: Frontiers Media S.A. 2015-02-01
Series:Frontiers in Oncology
Subjects:
SET
Online Access:http://journal.frontiersin.org/Journal/10.3389/fonc.2015.00021/full