T cell mediated pathogenesis in EAE: Molecular mechanisms

T cells are major initiators and mediators of disease in multiple sclerosis (MS) and in its animal model experimental autoimmune encephalomyelitis (EAE). EAE is an antigen-driven autoimmune model in which immunization against myelin autoantigens elicits strong T cell responses which initiate its pat...

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Bibliographic Details
Main Author: Florian C Kurschus
Format: Article
Language:English
Published: Elsevier 2015-06-01
Series:Biomedical Journal
Subjects:
CNS
EAE
Online Access:http://www.biomedj.org/article.asp?issn=2319-4170;year=2015;volume=38;issue=3;spage=183;epage=193;aulast=Kurschus