Omega-6 oxylipins generated by soluble epoxide hydrolase are associated with knee osteoarthritis

Omega-6 oxylipins generated by soluble epoxide hydrolase are associated with knee osteoarthritis

Omega-6 FAs are inflammatory mediators that are increased in joints with osteoarthritis (OA), but their association with OA progression is not yet well defined. To investigate the relationship between omega-6 FAs and knee OA, we measured with LC-MS the levels of 22 omega-6 lipids (arachidonic acid,...

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Bibliographic Details
Main Authors: Ana M. Valdes, Srinivasarao Ravipati, Petros Pousinis, Cristina Menni, Massimo Mangino, Abhishek Abhishek, Victoria Chapman, David A. Barrett, Michael Doherty
Format: Article
Language:English
Published: Elsevier 2018-09-01
Series:Journal of Lipid Research
Subjects:
lipids
arachidonic acid
eicosanoids
inflammation
methods/high-performance liquid chromatography
lipidomics
Online Access:http://www.sciencedirect.com/science/article/pii/S0022227520335458

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http://www.sciencedirect.com/science/article/pii/S0022227520335458

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