Oxidative burden and mitochondrial dysfunction in a mouse model of Rett syndrome

Oxidative burden and mitochondrial dysfunction in a mouse model of Rett syndrome

Rett syndrome is an X chromosome-linked neurodevelopmental disorder associated with cognitive impairment, motor dysfunction and breathing irregularities causing intermittent hypoxia. Evidence for impaired mitochondrial function is also accumulating. A subunit of complex III is among the potentially...

Full description

Bibliographic Details
Main Authors: Emanuel Großer, Ursula Hirt, Oliwia A. Janc, Christiane Menzfeld, Marc Fischer, Belinda Kempkes, Steffen Vogelgesang, Till U. Manzke, Lennart Opitz, Gabriela Salinas-Riester, Michael Müller
Format: Article
Language:English
Published: Elsevier 2012-10-01
Series:Neurobiology of Disease
Subjects:
Oxidative stress
Redox imbalance
Optical imaging
roGFP
Reactive oxygen species (ROS)
Microarray
Online Access:http://www.sciencedirect.com/science/article/pii/S0969996112002227

Internet

http://www.sciencedirect.com/science/article/pii/S0969996112002227

Similar Items