Allosteric signalling in the outer membrane translocation domain of PapC usher

Allosteric signalling in the outer membrane translocation domain of PapC usher

PapC ushers are outer-membrane proteins enabling assembly and secretion of P pili in uropathogenic E. coli. Their translocation domain is a large β-barrel occluded by a plug domain, which is displaced to allow the translocation of pilus subunits across the membrane. Previous studies suggested that t...

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Bibliographic Details
Main Authors: Irene Farabella, Thieng Pham, Nadine S Henderson, Sebastian Geibel, Gilles Phan, David G Thanassi, Anne H Delcour, Gabriel Waksman, Maya Topf
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2014-10-01
Series:eLife
Subjects:
dynamics
outer membrane protein
evolution
structure
Online Access:https://elifesciences.org/articles/03532

Internet

https://elifesciences.org/articles/03532

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