Control of Cytoskeletal Dynamics by β-Arrestin1/Myosin Vb Signaling Regulates Endosomal Sorting and Scavenging Activity of the Atypical Chemokine Receptor ACKR2

Control of Cytoskeletal Dynamics by β-Arrestin1/Myosin Vb Signaling Regulates Endosomal Sorting and Scavenging Activity of the Atypical Chemokine Receptor ACKR2

The atypical chemokine receptor ACKR2, formerly named D6, is a scavenger chemokine receptor with a non-redundant role in the control of inflammation and immunity. The scavenging activity of ACKR2 depends on its trafficking properties, which require actin cytoskeleton rearrangements downstream of a β...

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Bibliographic Details
Main Authors: Alessandro Vacchini, Cinzia Cancellieri, Samantha Milanesi, Sabrina Badanai, Benedetta Savino, Francesco Bifari, Massimo Locati, Raffaella Bonecchi, Elena Monica Borroni
Format: Article
Language:English
Published: MDPI AG 2020-09-01
Series:Vaccines
Subjects:
ACKR2
chemokine
β-arrestin1
cytoskeleton
myosin Vb
Online Access:https://www.mdpi.com/2076-393X/8/3/542

Internet

https://www.mdpi.com/2076-393X/8/3/542

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