Increased Oxidative Stress and Mitochondrial Dysfunction in Zucker Diabetic Rat Liver and Brain

Increased Oxidative Stress and Mitochondrial Dysfunction in Zucker Diabetic Rat Liver and Brain

Background/Aims: The Zucker diabetic fatty (ZDF, FA/FA) rat is a genetic model of type 2 diabetes, characterized by insulin resistance with progressive metabolic syndrome. We have previously demonstrated mitochondrial dysfunction and oxidative stress in the heart, kidneys and pancreas of ZDF rats. H...

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Bibliographic Details
Main Authors: Haider Raza, Annie John, Frank Christopher Howarth
Format: Article
Language:English
Published: Cell Physiol Biochem Press GmbH & Co KG 2015-02-01
Series:Cellular Physiology and Biochemistry
Subjects:
Oxidative stress
Mitochondrial dysfunction
Zucker diabetic rats
Liver
Brain
Online Access:http://www.karger.com/Article/FullText/373947

Internet

http://www.karger.com/Article/FullText/373947

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