Immune Checkpoints as the Immune System Regulators and Potential Biomarkers in HIV-1 Infection

Immune checkpoints are several co-stimulatory and inhibitory pathways that regulate T cell immune responses. Most of the discoveries about immune checkpoints were made in cancer research where inhibitory immune checkpoints cause immune exhaustion and down-regulate anti-tumor responses. In addition t...

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Bibliographic Details
Main Authors: Maike Sperk, Robert van Domselaar, Ujjwal Neogi
Format: Article
Language:English
Published: MDPI AG 2018-07-01
Series:International Journal of Molecular Sciences
Subjects:
Online Access:http://www.mdpi.com/1422-0067/19/7/2000