Combined Fluoxetine and Metformin Treatment Potentiates Antidepressant Efficacy Increasing IGF2 Expression in the Dorsal Hippocampus

An increasing number of studies show that selective serotonin reuptake inhibitors (SSRIs) exert their therapeutic action, at least in part, by amplifying the influence of the living environment on mood. As a consequence, when administered in a favorable environment, SSRIs lead to a reduction of symp...

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Main Authors: Silvia Poggini, Maria Teresa Golia, Silvia Alboni, Giampaolo Milior, Livio Pepè Sciarria, Aurelia Viglione, Gloria Matte Bon, Nicoletta Brunello, Stefano Puglisi-Allegra, Cristina Limatola, Laura Maggi, Igor Branchi
Format: Article
Language:English
Published: Hindawi Limited 2019-01-01
Series:Neural Plasticity
Online Access:http://dx.doi.org/10.1155/2019/4651031