Expression of Amyloid-Associated miRNAs in Both the Forebrain Cortex and Hippocampus of Middle-Aged Rat

Background: Aging is associated with the gradual cognitive decline and shows the typical senile plaque formation in the brain, which results from the aggregation of beta amyloid (Aβ) peptide following the abnormal proteolytic processing of amyloid precursor protein (APP) by β-secretase (BACE1) and &...

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Bibliographic Details
Main Authors: Hui Che, Li-Hua Sun, Fei Guo, Hui-Fang Niu, Xiao-Lin Su, Ya-Nan Bao, Zidong Donna Fu, Huai-lei Liu, Xu Hou, Bao-Feng Yang, Jing Ai
Format: Article
Language:English
Published: Cell Physiol Biochem Press GmbH & Co KG 2014-01-01
Series:Cellular Physiology and Biochemistry
Subjects:
APP
Online Access:http://www.karger.com/Article/FullText/356646