Bile acid metabolism and signaling in liver disease and therapy
Bile acids play a critical role in the regulation of glucose, lipid, and energy metabolism through activation of the nuclear bile acid receptor farnesoid X receptor (FXR) and membrane G protein-coupled bile acid receptor-1 (Gpbar-1, aka TGR5). Agonist activation of FXR and TGR5 improves insulin and...
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| Format: | Article |
| Language: | English |
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KeAi Communications Co., Ltd.
2017-06-01
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| Series: | Liver Research |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2542568417000071 |