Enhanced PRL-1 expression in placenta-derived mesenchymal stem cells accelerates hepatic function via mitochondrial dynamics in a cirrhotic rat model

Enhanced PRL-1 expression in placenta-derived mesenchymal stem cells accelerates hepatic function via mitochondrial dynamics in a cirrhotic rat model

Abstract Background Placenta-derived mesenchymal stem cells (PD-MSCs) have been highlighted as an alternative cell therapy agent that has become a next-generation stem cell treatment. Phosphatase of regenerating liver-1 (PRL-1), an immediate early gene, plays a critical role during liver regeneratio...

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Bibliographic Details
Main Authors: Jae Yeon Kim, Jong Ho Choi, Ji Hye Jun, Sohae Park, Jieun Jung, Si Hyun Bae, Gi Jin Kim
Format: Article
Language:English
Published: BMC 2020-11-01
Series:Stem Cell Research & Therapy
Subjects:
Chronic liver fibrosis
Mitochondria
Phosphatase of regenerating liver-1
Placenta-derived mesenchymal stem cells
Online Access:https://doi.org/10.1186/s13287-020-02029-3

Internet

https://doi.org/10.1186/s13287-020-02029-3

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