Identification of Key Phospholipids That Bind and Activate Atypical PKCs

Identification of Key Phospholipids That Bind and Activate Atypical PKCs

PKCζ and PKCι/λ form the atypical protein kinase C subgroup, characterised by a lack of regulation by calcium and the neutral lipid diacylglycerol. To better understand the regulation of these kinases, we systematically explored their interactions with various purified phospholipids using the lipid...

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Bibliographic Details
Main Authors: Suresh Velnati, Sara Centonze, Federico Girivetto, Daniela Capello, Ricardo M. Biondi, Alessandra Bertoni, Roberto Cantello, Beatrice Ragnoli, Mario Malerba, Andrea Graziani, Gianluca Baldanzi
Format: Article
Language:English
Published: MDPI AG 2021-01-01
Series:Biomedicines
Subjects:
membrane
lipid-protein interaction
lipid signalling
kinase regulation
phosphatidylinositols
Online Access:https://www.mdpi.com/2227-9059/9/1/45

Internet

https://www.mdpi.com/2227-9059/9/1/45

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