Clinical and Genetic Aspects of CADASIL

Cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL), a hereditary cerebral small vessel disease caused by mutations in NOTCH3, is characterized by recurrent stroke without vascular risk factors, mood disturbances, and dementia. MRI imaging shows cereb...

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Bibliographic Details
Main Authors: Toshiki Mizuno, Ikuko Mizuta, Akiko Watanabe-Hosomi, Mao Mukai, Takashi Koizumi
Format: Article
Published: Frontiers Media S.A. 2020-05-01
Series:Frontiers in Aging Neuroscience
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