Determinants of Phagosomal pH During Host-Pathogen Interactions

The ability of phagosomes to halt microbial growth is intimately linked to their ability to acidify their luminal pH. Establishment and maintenance of an acidic lumen requires precise co-ordination of H+ pumping and counter-ion permeation to offset the countervailing H+ leakage. Despite the best eff...

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Bibliographic Details
Main Authors: Johannes Westman, Sergio Grinstein
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-01-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
pH
Online Access:https://www.frontiersin.org/articles/10.3389/fcell.2020.624958/full