Gasdermin: A new player to the inflammasome game

Pyroptosis is a lytic type of programmed cell death that was traditionally associated with the involvement of inflammatory caspases, such as caspase-1. These inflammatory caspases are activated within multi-protein complexes called inflammasomes that are assembled in response to invading pathogens a...

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Bibliographic Details
Main Authors: Erivan S. Ramos-Junior, Ana Carolina Morandini
Format: Article
Language:English
Published: Elsevier 2017-12-01
Series:Biomedical Journal
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2319417017302780