Trichosanthin cooperates with Granzyme B to restrain tumor formation in tongue squamous cell carcinoma

Trichosanthin cooperates with Granzyme B to restrain tumor formation in tongue squamous cell carcinoma

Abstract Background Tongue squamous cell carcinoma (TSCC) is a common type of oral cancer, with a relatively poor prognosis and low post-treatment survival rate. Various strategies and novel drugs to treat TSCC are emerging and under investigation. Trichosanthin (TCS), extracted from the root tubers...

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Bibliographic Details
Main Authors: Zeyao Zhu, Zhenguang Ying, Meiqi Zeng, Qiang Zhang, Guiqing Liao, Yunliu Liang, Chunman Li, Chengfei Zhang, Xia Wang, Weipeng Jiang, Ping Luan, Ou Sha
Format: Article
Language:English
Published: BMC 2021-03-01
Series:BMC Complementary Medicine and Therapies
Subjects:
Apoptosis
Granzyme B (GrzB)
Oral squamous cell cancer (OSCC)
Tongue squamous cell cancer (TSCC)
Trichosanthin (TCS)
Online Access:https://doi.org/10.1186/s12906-021-03266-6

Internet

https://doi.org/10.1186/s12906-021-03266-6

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