Quantitative Structure – Pharmacokinetics Relationships for Plasma Protein Binding of Basic Drugs

Purpose. Binding of drugs to plasma proteins is a common physiological occurrence which may have a profound effect on both pharmacokinetics and pharmacodynamics. The early prediction of plasma protein binding (PPB) of new drug candidates is an important step in drug development process. The present...

Full description

Bibliographic Details
Main Author: Zvetanka Dobreva Zhivkova
Format: Article
Language:English
Published: Canadian Society for Pharmaceutical Sciences 2018-01-01
Series:Journal of Pharmacy & Pharmaceutical Sciences
Online Access:https://journals.library.ualberta.ca/jpps/index.php/JPPS/article/view/28971