Synthetic Nanoparticles That Promote Tumor Necrosis Factor Receptor 2 Expressing Regulatory T Cells in the Lung and Resistance to Allergic Airways Inflammation

Synthetic Nanoparticles That Promote Tumor Necrosis Factor Receptor 2 Expressing Regulatory T Cells in the Lung and Resistance to Allergic Airways Inflammation

Synthetic glycine coated 50 nm polystyrene nanoparticles (NP) (PS50G), unlike ambient NP, do not promote pulmonary inflammation, but instead, render lungs resistant to the development of allergic airway inflammation. In this study, we show that PS50G modulate the frequency and phenotype of regulator...

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Bibliographic Details
Main Authors: Rohimah Mohamud, Jeanne S. LeMasurier, Jennifer C. Boer, Je Lin Sieow, Jennifer M. Rolland, Robyn E. O’Hehir, Charles L. Hardy, Magdalena Plebanski
Format: Article
Language:English
Published: Frontiers Media S.A. 2017-12-01
Series:Frontiers in Immunology
Subjects:
nanoparticles
tumor necrosis factor 2
asthma
PS50G
lung
lymph nodes
Online Access:http://journal.frontiersin.org/article/10.3389/fimmu.2017.01812/full

Internet

http://journal.frontiersin.org/article/10.3389/fimmu.2017.01812/full

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