IL-12p40 deficiency leads to uncontrolled Trypanosoma cruzi dissemination in the spinal cord resulting in neuronal death and motor dysfunction.

IL-12p40 deficiency leads to uncontrolled Trypanosoma cruzi dissemination in the spinal cord resulting in neuronal death and motor dysfunction.

Chagas' disease is a protozoosis caused by Trypanosoma cruzi that frequently shows severe chronic clinical complications of the heart or digestive system. Neurological disorders due to T. cruzi infection are also described in children and immunosuppressed hosts. We have previously reported that...

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Bibliographic Details
Main Authors: André Luis Bombeiro, Lígia Antunes Gonçalves, Carlos Penha-Gonçalves, Claudio Romero Farias Marinho, Maria Regina D'Império Lima, Gerson Chadi, José Maria Álvarez
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/23152844/?tool=EBI

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https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/23152844/?tool=EBI

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