IL-12p40 deficiency leads to uncontrolled Trypanosoma cruzi dissemination in the spinal cord resulting in neuronal death and motor dysfunction.
Chagas' disease is a protozoosis caused by Trypanosoma cruzi that frequently shows severe chronic clinical complications of the heart or digestive system. Neurological disorders due to T. cruzi infection are also described in children and immunosuppressed hosts. We have previously reported that...
Main Authors: | André Luis Bombeiro, Lígia Antunes Gonçalves, Carlos Penha-Gonçalves, Claudio Romero Farias Marinho, Maria Regina D'Império Lima, Gerson Chadi, José Maria Álvarez |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2012-01-01
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Series: | PLoS ONE |
Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/23152844/?tool=EBI |
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