Plasmodium falciparum erythrocyte membrane protein 1 diversity in seven genomes--divide and conquer.

The var gene encoded hyper-variable Plasmodium falciparum erythrocyte membrane protein 1 (PfEMP1) family mediates cytoadhesion of infected erythrocytes to human endothelium. Antibodies blocking cytoadhesion are important mediators of malaria immunity acquired by endemic populations. The development...

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Bibliographic Details
Main Authors: Thomas S Rask, Daniel A Hansen, Thor G Theander, Anders Gorm Pedersen, Thomas Lavstsen
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-09-01
Series:PLoS Computational Biology
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/20862303/?tool=EBI