Development of a Novel ex vivo Nasal Epithelial Cell Model Supporting Colonization With Human Nasal Microbiota

Development of a Novel ex vivo Nasal Epithelial Cell Model Supporting Colonization With Human Nasal Microbiota

The nasal mucosa provides first line defense against inhaled pathogens while creating a unique microenvironment for bacterial communities. Studying the impact of microbiota in the nasal cavity has been difficult due to limitations with current models including explant cultures, primary cells, or neo...

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Bibliographic Details
Main Authors: Derald D. Charles, James R. Fisher, Sarah M. Hoskinson, Audrie A. Medina-Colorado, Yi C. Shen, Mohamad R. Chaaban, Steven G. Widen, Tonyia D. Eaves-Pyles, Carrie A. Maxwell, Aaron L. Miller, Vsevolod L. Popov, Richard B. Pyles
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-05-01
Series:Frontiers in Cellular and Infection Microbiology
Subjects:
nasal microbiome
nasal mucosa
culture model
respiratory system
human
Online Access:https://www.frontiersin.org/article/10.3389/fcimb.2019.00165/full

Internet

https://www.frontiersin.org/article/10.3389/fcimb.2019.00165/full

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